The identification of an osteoclastogenesis inhibitor through the inhibition of glyoxalase I

Osteoclasts, bone-resorptive multinucleated cells derived from hematopoietic stem cells, are associated with many bone-related diseases, such as osteoporosis. Osteoclast-targeting small-molecule inhibitors are valuable tools for studying osteoclast biology and for developing antiresorptive agents. H...

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Dettagli Bibliografici
Autori principali: Kawatani, Makoto, Okumura, Hideo, Honda, Kaori, Kanoh, Naoki, Muroi, Makoto, Dohmae, Naoshi, Takami, Masamichi, Kitagawa, Mitsuhiro, Futamura, Yushi, Imoto, Masaya, Osada, Hiroyuki
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2008
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575282/
https://ncbi.nlm.nih.gov/pubmed/18695250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0712239105
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