A small-molecule ligand of valosin-containing protein/p97 inhibits cancer cell–accelerated fibroblast migration

Carcinoma-associated fibroblasts are fibroblasts activated by surrounding cancer cells. Carcinoma-associated fibroblasts exhibit enhanced cell migration, which plays an important role in cancer metastasis. Previously, we demonstrated enhanced migration of NIH3T3 fibroblasts when they were cultured i...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Suvarna, Kruthi, Honda, Kaori, Muroi, Makoto, Kondoh, Yasumitsu, Osada, Hiroyuki, Watanabe, Nobumoto
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2019
Subjects:
Molecular Bases of Disease
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6398144/
https://ncbi.nlm.nih.gov/pubmed/30610116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.004741
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