Intratumoral Immunocytokine Treatment Results in Enhanced Antitumor Effects

Immunocytokines (IC), consisting of tumor-specific monoclonal antibodies fused to the immunostimulatory cytokine interleukin 2 (IL2), exert significant antitumor effects in several murine tumor models. We investigated whether intratumoral (IT) administration of IC provided enhanced antitumor effects...

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Autors principals: Johnson, Erik E., Lum, Hillary D., Rakhmilevich, Alexander L., Schmidt, Brian E., Furlong, Meghan, Buhtoiarov, Ilia N., Hank, Jacquelyn A., Raubitschek, Andrew, Colcher, David, Reisfeld, Ralph A., Gillies, Stephen D., Sondel, Paul M.
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2574976/
https://ncbi.nlm.nih.gov/pubmed/18438664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-008-0519-0
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