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Machine Learning Methods and Docking For Predicting Human Pregnane X Receptor Activation
The pregnane X receptor (PXR) regulates the expression of genes involved in xenobiotic metabolism and transport. In vitro methods to screen for PXR agonists are used widely. In the current study, computational models for human PXR activators and PXR non-activators were developed using recursive part...
Gorde:
| Egile Nagusiak: | , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2008
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2574557/ https://ncbi.nlm.nih.gov/pubmed/18547065 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx800102e |
| Etiketak: |
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