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Functional evolution of the vitamin D and pregnane X receptors

BACKGROUND: The vitamin D receptor (VDR) and pregnane X receptor (PXR) are nuclear hormone receptors of the NR1I subfamily that show contrasting patterns of cross-species variation. VDR and PXR are thought to have arisen from duplication of an ancestral gene, evident now as a single gene in the geno...

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Detalhes bibliográficos
Main Authors: Reschly, Erica J, Bainy, Afonso Celso Dias, Mattos, Jaco Joaquim, Hagey, Lee R, Bahary, Nathan, Mada, Sripal R, Ou, Junhai, Venkataramanan, Raman, Krasowski, Matthew D
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2263054/
https://ncbi.nlm.nih.gov/pubmed/17997857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-7-222
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