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Functional evolution of the pregnane X receptor
The pregnane X receptor (PXR; NR1I2) is a nuclear hormone receptor (NR) that transcriptionally regulates genes encoding transporters and drug-metabolizing enzymes in the liver and intestine. PXR activation leads to enhanced metabolism and elimination of xenobiotics and endogenous compounds such as h...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2231407/ https://ncbi.nlm.nih.gov/pubmed/16863441 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/17425255.2.3.381 |
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