Efficacy of Single-Dose Liposomal Amphotericin B or Micafungin Prophylaxis in a Neutropenic Murine Model of Invasive Pulmonary Aspergillosis

In a neutropenic murine model of invasive pulmonary aspergillosis, prophylaxis with single doses of liposomal amphotericin B or micafungin at ≥5 mg/kg of body weight improved animal survival and suppressed the lung fungal burden for up to 7 days after infection, demonstrating the potential utility o...

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Hlavní autoři: Lewis, Russell E., Albert, Nathaniel D., Kontoyiannis, Dimitrios P.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2008
Témata:
Experimental Therapeutics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2573155/
https://ncbi.nlm.nih.gov/pubmed/18725439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00715-08
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