Comparative Pharmacodynamics of Amphotericin B Lipid Complex and Liposomal Amphotericin B in a Murine Model of Pulmonary Mucormycosis

We compared the kinetics of amphotericin B (AMB) lung accumulation and fungal clearance by liposomal amphotericin B (L-AMB) and amphotericin B lipid complex (ABLC) in a neutropenic murine model of invasive pulmonary mucormycosis (IPM). Immunosuppressed BALB/c mice were inoculated with 1 × 10(6) Rhiz...

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Bibliografische gegevens
Hoofdauteurs: Lewis, Russell E., Albert, Nathan D., Liao, Guangling, Hou, Jingguo, Prince, Randall A., Kontoyiannis, Dimitrios P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology (ASM) 2010
Onderwerpen:
Experimental Therapeutics
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2826015/
https://ncbi.nlm.nih.gov/pubmed/20038620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01222-09
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