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Membrane translocation of diphtheria toxin carrying passenger protein domains.

For diphtheria toxin to be cytotoxic, the enzymatically active part (fragment A) must be translocated to the cytosol. We here demonstrate that additional proteins linked as N-terminal extensions can be translocated along with fragment A across the plasma membrane of toxin-sensitive cells. Thus, an e...

Täydet tiedot

Tallennettuna:
Julkaisussa:Infect Immun
Päätekijät: Madshus, I H, Olsnes, S, Stenmark, H
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology (ASM) 1992
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC257314/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1639497/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.60.8.3296-3302.1992
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