Membrane translocation of diphtheria toxin carrying passenger protein domains.
For diphtheria toxin to be cytotoxic, the enzymatically active part (fragment A) must be translocated to the cytosol. We here demonstrate that additional proteins linked as N-terminal extensions can be translocated along with fragment A across the plasma membrane of toxin-sensitive cells. Thus, an e...
Guardat en:
| Publicat a: | Infect Immun |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology (ASM)
1992
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC257314/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1639497/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.60.8.3296-3302.1992 |
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