Membrane translocation of diphtheria toxin carrying passenger protein domains.

For diphtheria toxin to be cytotoxic, the enzymatically active part (fragment A) must be translocated to the cytosol. We here demonstrate that additional proteins linked as N-terminal extensions can be translocated along with fragment A across the plasma membrane of toxin-sensitive cells. Thus, an e...

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Pubblicato in:	Infect Immun
Autori principali:	Madshus, I H, Olsnes, S, Stenmark, H
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1992
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC257314/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1639497/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.60.8.3296-3302.1992
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