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Membrane translocation of diphtheria toxin carrying passenger protein domains.

For diphtheria toxin to be cytotoxic, the enzymatically active part (fragment A) must be translocated to the cytosol. We here demonstrate that additional proteins linked as N-terminal extensions can be translocated along with fragment A across the plasma membrane of toxin-sensitive cells. Thus, an e...

詳細記述

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書誌詳細
主要な著者: Madshus, I H, Olsnes, S, Stenmark, H
フォーマット: Artigo
言語:Inglês
出版事項: 1992
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC257314/
https://ncbi.nlm.nih.gov/pubmed/1639497
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