Metronidazole Lacks Antibacterial Activity in Guinea Pigs Infected with Mycobacterium tuberculosis

Metronidazole, which is used for the treatment of infections caused by anaerobic organisms, was evaluated in Mycobacterium tuberculosis-infected guinea pigs. M. tuberculosis can adapt to hypoxia, which is present in the primary lesions of infected guinea pigs. Metronidazole treatment (for 6 weeks at...

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Autors principals: Hoff, Donald R., Caraway, Megan L., Brooks, Elizabeth J., Driver, Emily R., Ryan, Gavin J., Peloquin, Charles A., Orme, Ian M., Basaraba, Randall J., Lenaerts, Anne J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2008
Matèries:
Experimental Therapeutics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2573095/
https://ncbi.nlm.nih.gov/pubmed/18694944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00196-08
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