Oral Therapy Using Nanoparticle-Encapsulated Antituberculosis Drugs in Guinea Pigs Infected with Mycobacterium tuberculosis

We evaluated the efficacy of nanoparticle-encapsulated antituberculosis drugs administered every 10 days versus that of daily nonencapsulated drugs against Mycobacterium tuberculosis aerosol infection in guinea pigs. Both treatments significantly reduced the bacterial count and lung histopathology,...

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Detalhes bibliográficos
Main Authors: Johnson, Christine M., Pandey, Rajesh, Sharma, Sadhna, Khuller, G. K., Basaraba, Randall J., Orme, Ian M., Lenaerts, Anne J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1251542/
https://ncbi.nlm.nih.gov/pubmed/16189115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.10.4335-4338.2005
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