Activities of TMC207, Rifampin, and Pyrazinamide against Mycobacterium tuberculosis Infection in Guinea Pigs

The experimental compound TMC207 is showing promise against infections caused by Mycobacterium tuberculosis both in a variety of animal studies and in the field. In this study, we used the guinea pig model, a species that shows several similarities to human tuberculosis, including the hallmark of pr...

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Dettagli Bibliografici
Autori principali: Shang, Shaobin, Shanley, Crystal A., Caraway, Megan L., Orme, Eileen A., Henao-Tamayo, Marcela, Hascall-Dove, Laurel, Ackart, David, Lenaerts, Anne J., Basaraba, Randall J., Orme, Ian M., Ordway, Diane J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2011
Soggetti:
Experimental Therapeutics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3019667/
https://ncbi.nlm.nih.gov/pubmed/20937788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00978-10
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