Drug Treatment Combined with BCG Vaccination Reduces Disease Reactivation in Guinea Pigs Infected with Mycobacterium tuberculosis

Bacillus-Calmette-Guerin (BCG), the only human tuberculosis vaccine, primes a partially protective immune response against M. tuberculosis infection in humans and animals. In guinea pigs, BCG vaccination slows the progression of disease and reduces the severity of necrotic granulomas, which harbor a...

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Autores principales: Shang, Shaobin, Shanley, Crystal A., Caraway, Megan L., Orme, Eileen A., Henao-Tamayo, Marcela, Hascall-Dove, Laurel, Ackart, David, Orme, Ian M., Ordway, Diane J., Basaraba, Randall J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3286658/
https://ncbi.nlm.nih.gov/pubmed/22244979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2011.12.114
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