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Drug Treatment Combined with BCG Vaccination Reduces Disease Reactivation in Guinea Pigs Infected with Mycobacterium tuberculosis

Bacillus-Calmette-Guerin (BCG), the only human tuberculosis vaccine, primes a partially protective immune response against M. tuberculosis infection in humans and animals. In guinea pigs, BCG vaccination slows the progression of disease and reduces the severity of necrotic granulomas, which harbor a...

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Detalhes bibliográficos
Main Authors: Shang, Shaobin, Shanley, Crystal A., Caraway, Megan L., Orme, Eileen A., Henao-Tamayo, Marcela, Hascall-Dove, Laurel, Ackart, David, Orme, Ian M., Ordway, Diane J., Basaraba, Randall J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3286658/
https://ncbi.nlm.nih.gov/pubmed/22244979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2011.12.114
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