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A Toll-Like Receptor-2-Directed Fusion Protein Vaccine against Tuberculosis
A fusion protein designated CSU-F36 was constructed that consisted of acylated Rv1411, a potent Toll-like receptor-2 agonist, fused to ESAT-6, a well-characterized immunogenic protein from Mycobacterium tuberculosis. The CSU-F36 fusion protein strongly induced interleukin 12 secretion from macrophag...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1951063/ https://ncbi.nlm.nih.gov/pubmed/17616633 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00077-07 |
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