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Immunopathogenesis of Pulmonary Granulomas in the Guinea Pig after Infection with Mycobacterium tuberculosis

Pulmonary tuberculosis in guinea pigs is similar to the disease in humans and is accordingly widely used as a model to test tuberculosis vaccines. The primary site of expression of acquired immunity and the hallmark of tuberculosis is the granuloma. Granuloma morphology is well described, but there...

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Detalhes bibliográficos
Main Authors: Turner, Oliver C., Basaraba, Randall J., Orme, Ian M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC145351/
https://ncbi.nlm.nih.gov/pubmed/12540568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.2.864-871.2003
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