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Amyloid Precursor Protein Trafficking, Processing, and Function

Intracellular trafficking and proteolytic processing of amyloid precursor protein (APP) have been the focus of numerous investigations over the past two decades. APP is the precursor to the amyloid β-protein (Aβ), the 38–43-amino acid residue peptide that is at the heart of the amyloid cascade hypot...

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Bibliografiske detaljer
Main Authors: Thinakaran, Gopal, Koo, Edward H.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2573065/
https://ncbi.nlm.nih.gov/pubmed/18650430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R800019200
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