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Transcription of DNA Containing the 5-Guanidino-4-nitroimidazole Lesion by Human RNA Polymerase II and Bacteriophage T7 RNA Polymerase

Damage in transcribed DNA presents a challenge to the cell because it can partially or completely block the progression of an RNA polymerase, interfering with transcription and compromising gene expression. While blockage of RNA polymerase progression is thought to trigger the recruitment of the tra...

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Autores principales: Dimitri, Alexandra, Jia, Lei, Shafirovich, Vladimir, Geacintov, Nicholas E., Broyde, Suse, Scicchitano, David A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2572817/
https://ncbi.nlm.nih.gov/pubmed/18555749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2008.04.007
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