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Characterization of Functional Heme Domains from Soluble Guanylate Cyclase
Soluble guanylate cyclase (sGC) is a heterodimeric, nitric oxide (NO)-sensing hemoprotein composed of two subunits, α1 and β1. NO binds to the heme cofactor in the β1 subunit, forming a 5-coordinate NO complex that activates the enzyme several hundred-fold. In this report the heme domain has been lo...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2572136/ https://ncbi.nlm.nih.gov/pubmed/16331987 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi051601b |
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