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Methylation of CIITA promoter IV causes loss of HLA-II inducibility by IFN-γ in promyelocytic cells
The human promyelocytic cell line THP-1 expresses high level of HLA class II (HLA-II) molecules after IFN-γ treatment. Here, we report a variant of THP-1 that does not express HLA-II after IFN-γ. The variant's HLA-II phenotype is constant over time in culture and it is not related to a defectiv...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2572003/ https://ncbi.nlm.nih.gov/pubmed/18829986 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intimm/dxn103 |
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