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Role of PKCδ in IFN-γ-inducible CIITA gene expression

The class II transactivator (CIITA) is a key regulatory factor for MHC class II expression. Here, we demonstrate that PKCδ plays an important role in regulating IFN-γ-inducible CIITA gene expression in macrophages. Inhibition of PKCδ by either a PKCδ inhibitor or a dominant negative (DN) mutant form...

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Detalhes bibliográficos
Main Authors: Kwon, Myung-Ja, Yao, Yongxue, Walter, Michael J., Holtzman, Michael J., Chang, Cheong-Hee
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1924468/
https://ncbi.nlm.nih.gov/pubmed/17346795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2007.01.035
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