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The IFN-γ-induced Transcriptional Program of the CIITA Gene is Inhibited by Statins
Statins are 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors that exert anti-inflammatory effects. IFN-γ induction of class II MHC expression, which requires the class II transactivator (CIITA), is inhibited by statins, however, the molecular basis for suppression is undetermined...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2692880/ https://ncbi.nlm.nih.gov/pubmed/18601229 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200838189 |
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