LPS induces CD40 gene expression through the activation of NF-κB and STAT-1α in macrophages and microglia

CD40 is expressed on various immune cells, including macrophages and microglia. Aberrant expression of CD40 is associated with autoimmune inflammatory diseases such as multiple sclerosis and rheumatoid arthritis. Interaction of Toll-like receptor-4 (TLR4) with the Gram-negative bacteria endotoxin li...

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Bibliografiske detaljer
Main Authors: Qin, Hongwei, Wilson, Cynthia A., Lee, Sun Jung, Zhao, Xueyan, Benveniste, Etty N.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society of Hematology 2005
Fag:
Immunobiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895321/
https://ncbi.nlm.nih.gov/pubmed/16020513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-02-0759
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