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Activation of the NF-κB pathway by the STAT3 inhibitor JSI-124 in human glioblastoma cells

Glioblastoma tumors are characterized by their invasiveness and resistance to therapies. The transcription factor STAT3 was recently identified as a master transcriptional regulator in the mesenchymal subtype of GBM, which has generated an increased interest in targeting STAT3. We have evaluated mor...

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Detalhes bibliográficos
Main Authors: McFarland, Braden C., Gray, G. Kenneth, Nozell, Susan E., Hong, Suk W., Benveniste, Etty N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3656973/
https://ncbi.nlm.nih.gov/pubmed/23386688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-12-0528
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