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NF-κB-Induced IL-6 Ensures STAT3 Activation and Tumor Aggressiveness in Glioblastoma

Glioblastoma (GBM) is the most aggressive, neurologically destructive and deadly tumor of the central nervous system (CNS). In GBM, the transcription factors NF-κB and STAT3 are aberrantly activated and associated with tumor cell proliferation, survival, invasion and chemoresistance. In addition, co...

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Bibliografiske detaljer
Main Authors: McFarland, Braden C., Hong, Suk W., Rajbhandari, Rajani, Twitty, George B., Gray, G. Kenneth, Yu, Hao, Benveniste, Etty N., Nozell, Susan E.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3823708/
https://ncbi.nlm.nih.gov/pubmed/24244348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0078728
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