Loss of tumor suppressive microRNA-31 enhances TRADD/NF-κB signaling in glioblastoma

Glioblastomas (GBMs) are deadly tumors of the central nervous system. Most GBM exhibit homozygous deletions of the CDKN2A and CDKN2B tumor suppressors at 9p21.3, although loss of CDKN2A/B alone is insufficient to drive gliomagenesis. MIR31HG, which encodes microRNA-31 (miR-31), is a novel non-coding...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Rajbhandari, Rajani, McFarland, Braden C., Patel, Ashish, Gerigk, Magda, Gray, G. Kenneth, Fehling, Samuel C., Bredel, Markus, Berbari, Nicolas F., Kim, Hyunsoo, Marks, Margaret P., Meares, Gordon P., Sinha, Tanvi, Chuang, Jeffrey, Benveniste, Etty N., Nozell, Susan E.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4627347/
https://ncbi.nlm.nih.gov/pubmed/26164206
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