Loss of tumor suppressive microRNA-31 enhances TRADD/NF-κB signaling in glioblastoma

Glioblastomas (GBMs) are deadly tumors of the central nervous system. Most GBM exhibit homozygous deletions of the CDKN2A and CDKN2B tumor suppressors at 9p21.3, although loss of CDKN2A/B alone is insufficient to drive gliomagenesis. MIR31HG, which encodes microRNA-31 (miR-31), is a novel non-coding...

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Pubblicato in:Oncotarget
Autori principali: Rajbhandari, Rajani, McFarland, Braden C., Patel, Ashish, Gerigk, Magda, Gray, G. Kenneth, Fehling, Samuel C., Bredel, Markus, Berbari, Nicolas F., Kim, Hyunsoo, Marks, Margaret P., Meares, Gordon P., Sinha, Tanvi, Chuang, Jeffrey, Benveniste, Etty N., Nozell, Susan E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2015
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4627347/
https://ncbi.nlm.nih.gov/pubmed/26164206
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