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CIITA-related block of HLA class II expression, upregulation of HLA class I, and heterogeneous expression of immune checkpoints in hepatocarcinomas: implications for new therapeutic approaches

Hepatocellular carcinoma (HCC) is the second cause of death for cancer worldwide, justifying the urgent need for novel therapeutic approaches. Immunotherapeutic strategies based on triggering and/or rescuing tumor antigen-specific T cells may be promising particularly if combined together. As prelim...

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Publicat a:Oncoimmunology
Autors principals: Ramia, Elise, Chiaravalli, Anna Maria, Bou Nasser Eddine, Farah, Tedeschi, Alessandra, Sessa, Fausto, Accolla, Roberto S., Forlani, Greta
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6350839/
https://ncbi.nlm.nih.gov/pubmed/30723578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2018.1548243
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