CIITA-related block of HLA class II expression, upregulation of HLA class I, and heterogeneous expression of immune checkpoints in hepatocarcinomas: implications for new therapeutic approaches

Hepatocellular carcinoma (HCC) is the second cause of death for cancer worldwide, justifying the urgent need for novel therapeutic approaches. Immunotherapeutic strategies based on triggering and/or rescuing tumor antigen-specific T cells may be promising particularly if combined together. As prelim...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Ramia, Elise, Chiaravalli, Anna Maria, Bou Nasser Eddine, Farah, Tedeschi, Alessandra, Sessa, Fausto, Accolla, Roberto S., Forlani, Greta
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6350839/
https://ncbi.nlm.nih.gov/pubmed/30723578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2018.1548243
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