CIITA-driven MHC class II expressing tumor cells can efficiently prime naive CD4(+) TH cells in vivo and vaccinate the host against parental MHC-II-negative tumor cells

Our previous studies showed that non-immunogenic H-2(d) tumor cells of distinct epithelial histotypes can become highly immunogenic, induce a protective CD4(+) T cell response and vaccinate the animals against parental MHC-II-negative cells if they are rendered MHC class II-positive by stable transf...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Bou Nasser Eddine, Farah, Forlani, Greta, Lombardo, Letizia, Tedeschi, Alessandra, Tosi, Giovanna, Accolla, Roberto S.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5283634/
https://ncbi.nlm.nih.gov/pubmed/28197387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1261777
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