Protective effects of a leukotriene inhibitor and a leukotriene antagonist on endotoxin-induced mortality in carrageenan-pretreated mice.

The leukotrienes and tumor necrosis factor (TNF) play an important role in the pathophysiology of septic shock, in which hypotension, leukopenia, thrombocytopenia, and hemoconcentration are observed. This study was performed to examine the effects of a 5-lipoxygenase inhibitor (AA-861), a selective...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Ogata, M, Matsumoto, T, Kamochi, M, Yoshida, S I, Mizuguchi, Y, Shigematsu, A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC257177/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1587610/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.60.6.2432-2437.1992
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