Protective effects of a leukotriene inhibitor and a leukotriene antagonist on endotoxin-induced mortality in carrageenan-pretreated mice.

The leukotrienes and tumor necrosis factor (TNF) play an important role in the pathophysiology of septic shock, in which hypotension, leukopenia, thrombocytopenia, and hemoconcentration are observed. This study was performed to examine the effects of a 5-lipoxygenase inhibitor (AA-861), a selective...

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Dades bibliogràfiques

Publicat a:	Infect Immun
Autors principals:	Ogata, M, Matsumoto, T, Kamochi, M, Yoshida, S I, Mizuguchi, Y, Shigematsu, A
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology (ASM) 1992
Matèries:	Research Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC257177/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1587610/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.60.6.2432-2437.1992
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