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Protective effects of a leukotriene inhibitor and a leukotriene antagonist on endotoxin-induced mortality in carrageenan-pretreated mice.

The leukotrienes and tumor necrosis factor (TNF) play an important role in the pathophysiology of septic shock, in which hypotension, leukopenia, thrombocytopenia, and hemoconcentration are observed. This study was performed to examine the effects of a 5-lipoxygenase inhibitor (AA-861), a selective...

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Bibliografische gegevens
Hoofdauteurs: Ogata, M, Matsumoto, T, Kamochi, M, Yoshida, S I, Mizuguchi, Y, Shigematsu, A
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1992
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC257177/
https://ncbi.nlm.nih.gov/pubmed/1587610
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