Protective effects of a leukotriene inhibitor and a leukotriene antagonist on endotoxin-induced mortality in carrageenan-pretreated mice.

The leukotrienes and tumor necrosis factor (TNF) play an important role in the pathophysiology of septic shock, in which hypotension, leukopenia, thrombocytopenia, and hemoconcentration are observed. This study was performed to examine the effects of a 5-lipoxygenase inhibitor (AA-861), a selective...

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Pubblicato in:	Infect Immun
Autori principali:	Ogata, M, Matsumoto, T, Kamochi, M, Yoshida, S I, Mizuguchi, Y, Shigematsu, A
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1992
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC257177/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1587610/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.60.6.2432-2437.1992
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