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Protective effects of a leukotriene inhibitor and a leukotriene antagonist on endotoxin-induced mortality in carrageenan-pretreated mice.

The leukotrienes and tumor necrosis factor (TNF) play an important role in the pathophysiology of septic shock, in which hypotension, leukopenia, thrombocytopenia, and hemoconcentration are observed. This study was performed to examine the effects of a 5-lipoxygenase inhibitor (AA-861), a selective...

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Bibliografski detalji
Izdano u:Infect Immun
Glavni autori: Ogata, M, Matsumoto, T, Kamochi, M, Yoshida, S I, Mizuguchi, Y, Shigematsu, A
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 1992
Teme:
Online pristup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC257177/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1587610/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.60.6.2432-2437.1992
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