p16(INK4a) Expression and Absence of Activated B-RAF Are Independent Predictors of Chemosensitivity in Melanoma Tumors

Metastatic cutaneous melanoma is highly resistant to cytotoxic drugs, and this contributes to poor prognosis. In vivo studies on the chemosensitivity of metastatic melanoma are rare and hampered by poor response rates to systemic chemotherapeutics. Patients who undergo isolated limb infusion (ILI) w...

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Main Authors: Gallagher, Stuart J, Thompson, John F, Indsto, James, Scurr, Lyndee L, Lett, Margaret, Gao, Bo-Fu, Dunleavey, Ruth, Mann, Graham J, Kefford, Richard F, Rizos, Helen
格式: Artigo
語言:Inglês
出版: Neoplasia Press Inc. 2008
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2570599/
https://ncbi.nlm.nih.gov/pubmed/18953432
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