p16(INK4a) Expression and Absence of Activated B-RAF Are Independent Predictors of Chemosensitivity in Melanoma Tumors

Metastatic cutaneous melanoma is highly resistant to cytotoxic drugs, and this contributes to poor prognosis. In vivo studies on the chemosensitivity of metastatic melanoma are rare and hampered by poor response rates to systemic chemotherapeutics. Patients who undergo isolated limb infusion (ILI) w...

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Библиографические подробности
Главные авторы: Gallagher, Stuart J, Thompson, John F, Indsto, James, Scurr, Lyndee L, Lett, Margaret, Gao, Bo-Fu, Dunleavey, Ruth, Mann, Graham J, Kefford, Richard F, Rizos, Helen
Формат: Artigo
Язык:Inglês
Опубликовано: Neoplasia Press Inc. 2008
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2570599/
https://ncbi.nlm.nih.gov/pubmed/18953432
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