p16(INK4a) Expression and Absence of Activated B-RAF Are Independent Predictors of Chemosensitivity in Melanoma Tumors

Metastatic cutaneous melanoma is highly resistant to cytotoxic drugs, and this contributes to poor prognosis. In vivo studies on the chemosensitivity of metastatic melanoma are rare and hampered by poor response rates to systemic chemotherapeutics. Patients who undergo isolated limb infusion (ILI) w...

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Detalhes bibliográficos
Main Authors: Gallagher, Stuart J, Thompson, John F, Indsto, James, Scurr, Lyndee L, Lett, Margaret, Gao, Bo-Fu, Dunleavey, Ruth, Mann, Graham J, Kefford, Richard F, Rizos, Helen
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2570599/
https://ncbi.nlm.nih.gov/pubmed/18953432
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