p16(INK4a) Expression and Absence of Activated B-RAF Are Independent Predictors of Chemosensitivity in Melanoma Tumors

Metastatic cutaneous melanoma is highly resistant to cytotoxic drugs, and this contributes to poor prognosis. In vivo studies on the chemosensitivity of metastatic melanoma are rare and hampered by poor response rates to systemic chemotherapeutics. Patients who undergo isolated limb infusion (ILI) w...

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Autors principals: Gallagher, Stuart J, Thompson, John F, Indsto, James, Scurr, Lyndee L, Lett, Margaret, Gao, Bo-Fu, Dunleavey, Ruth, Mann, Graham J, Kefford, Richard F, Rizos, Helen
Format: Artigo
Idioma:Inglês
Publicat: Neoplasia Press Inc. 2008
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2570599/
https://ncbi.nlm.nih.gov/pubmed/18953432
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