The chromatin remodelling factor BRG1 is a novel binding partner of the tumor suppressor p16(INK4a)

BACKGROUND: CDKN2A/p16(INK4a )is frequently altered in human cancers and it is the most important melanoma susceptibility gene identified to date. p16(INK4a )inhibits pRb phosphorylation and induces cell cycle arrest, which is considered its main tumour suppressor function. Nevertheless, additional...

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Detalhes bibliográficos
Main Authors: Becker, Therese M, Haferkamp, Sebastian, Dijkstra, Menno K, Scurr, Lyndee L, Frausto, Monika, Diefenbach, Eve, Scolyer, Richard A, Reisman, David N, Mann, Graham J, Kefford, Richard F, Rizos, Helen
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2644676/
https://ncbi.nlm.nih.gov/pubmed/19149898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-8-4
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