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The chromatin remodelling factor BRG1 is a novel binding partner of the tumor suppressor p16(INK4a)

BACKGROUND: CDKN2A/p16(INK4a )is frequently altered in human cancers and it is the most important melanoma susceptibility gene identified to date. p16(INK4a )inhibits pRb phosphorylation and induces cell cycle arrest, which is considered its main tumour suppressor function. Nevertheless, additional...

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Bibliografische gegevens
Hoofdauteurs: Becker, Therese M, Haferkamp, Sebastian, Dijkstra, Menno K, Scurr, Lyndee L, Frausto, Monika, Diefenbach, Eve, Scolyer, Richard A, Reisman, David N, Mann, Graham J, Kefford, Richard F, Rizos, Helen
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2009
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2644676/
https://ncbi.nlm.nih.gov/pubmed/19149898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-8-4
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