β-Blockers alprenolol and carvedilol stimulate β-arrestin-mediated EGFR transactivation

Recent evidence suggests that binding of agonist to its cognate receptor initiates not only classical G protein-mediated signaling, but also β-arrestin-dependent signaling. One such β-arrestin-mediated pathway uses the β(1)-adrenergic receptor (β(1)AR) to transactivate the EGFR. To determine whether...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Kim, Il-Man, Tilley, Douglas G., Chen, Juhsien, Salazar, Natasha C., Whalen, Erin J., Violin, Jonathan D., Rockman, Howard A.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2008
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2567217/
https://ncbi.nlm.nih.gov/pubmed/18787115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0804745105
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars