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β-Arrestin Mediates β1-Adrenergic Receptor-Epidermal Growth Factor Receptor Interaction and Downstream Signaling

β1-Adrenergic receptor (β1AR) stimulation confers cardioprotection via β-arrestin-de pend ent transactivation of epidermal growth factor receptors (EGFRs), however, the precise mechanism for this salutary process is unknown. We tested the hypothesis that the β1AR and EGFR form a complex that differe...

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Detalhes bibliográficos
Main Authors: Tilley, Douglas G., Kim, Il-Man, Patel, Priyesh A., Violin, Jonathan D., Rockman, Howard A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2740462/
https://ncbi.nlm.nih.gov/pubmed/19509284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.005793
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