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β-Arrestin-2 Counters CXCR7-mediated EGFR Transactivation and Proliferation()

The atypical 7-transmebrane chemokine receptor, CXCR7 transactivates the epidermal growth factor receptor (EGFR) leading to increased tumor growth in several tumor types. However, the molecular mechanism of CXCR7-ligand independent EGFR-trans-activation is unknown. We used cDNA knock-in, RNA interfe...

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Bibliografski detalji
Izdano u:Mol Cancer Res
Glavni autori: Kallifatidis, Georgios, Munoz, Daniel, Singh, Rajendra Kumar, Salazar, Nicole, Hoy, James J., Lokeshwar, Bal L.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4867265/
https://ncbi.nlm.nih.gov/pubmed/26921391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-15-0498
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