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β-Arrestin-2 Counters CXCR7-mediated EGFR Transactivation and Proliferation()
The atypical 7-transmebrane chemokine receptor, CXCR7 transactivates the epidermal growth factor receptor (EGFR) leading to increased tumor growth in several tumor types. However, the molecular mechanism of CXCR7-ligand independent EGFR-trans-activation is unknown. We used cDNA knock-in, RNA interfe...
Enregistré dans:
| Publié dans: | Mol Cancer Res |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4867265/ https://ncbi.nlm.nih.gov/pubmed/26921391 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-15-0498 |
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