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Use of experimental crystallographic phases to examine the hydration of polar and nonpolar cavities in T4 lysozyme
There is conflicting evidence as to whether cavities in proteins that are nonpolar and large enough to accommodate solvent are empty or are occupied by disordered water molecules. Here, we use multiple-wavelength x-ray data collected from crystals of the selenomethionine-substituted L99A/M102L mutan...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2567155/ https://ncbi.nlm.nih.gov/pubmed/18780783 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0806307105 |
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