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Cooperative water filling of a nonpolar protein cavity observed by high-pressure crystallography and simulation
Formation of a water-expelling nonpolar core is the paradigm of protein folding and stability. Although experiment largely confirms this picture, water buried in “hydrophobic” cavities is required for the function of some proteins. Hydration of the protein core has also been suggested as the mechani...
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| Główni autorzy: | , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
National Academy of Sciences
2005
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1283839/ https://ncbi.nlm.nih.gov/pubmed/16269539 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0508224102 |
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