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Structural rigidity of a large cavity-containing protein revealed by high-pressure crystallography

Steric constraints, charged interactions and many other forces important to protein structure and function can be explored by mutagenic experiments. Research of this kind has led to a wealth of knowledge about what stabilizes proteins in their folded states. To gain a more complete picture requires...

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Detalhes bibliográficos
Main Authors: Collins, Marcus D., Quillin, Michael L., Hummer, Gerhard, Matthews, Brian W., Gruner, Sol M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1853337/
https://ncbi.nlm.nih.gov/pubmed/17292912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2006.12.021
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