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Determination of solvent content in cavities in IL-1β using experimentally phased electron density
The extent to which water is present within apolar cavities in proteins remains unclear. In the case of interleukin-1β (IL-1β), four independent structures solved by x-ray crystallography indicate that water is not present in the central apolar cavity. In contrast, results from NMR spectroscopy sugg...
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| Główni autorzy: | , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
National Academy of Sciences
2006
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1750907/ https://ncbi.nlm.nih.gov/pubmed/17179045 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0609442104 |
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