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Role of cavities and hydration in the pressure unfolding of T(4) lysozyme

It is well known that high hydrostatic pressures can induce the unfolding of proteins. The physical underpinnings of this phenomenon have been investigated extensively but remain controversial. Changes in solvation energetics have been commonly proposed as a driving force for pressure-induced unfold...

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Bibliografische gegevens
Hoofdauteurs: Nucci, Nathaniel V., Fuglestad, Brian, Athanasoula, Evangelia A., Wand, A. Joshua
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183293/
https://ncbi.nlm.nih.gov/pubmed/25201963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1410655111
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