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Role of cavities and hydration in the pressure unfolding of T(4) lysozyme
It is well known that high hydrostatic pressures can induce the unfolding of proteins. The physical underpinnings of this phenomenon have been investigated extensively but remain controversial. Changes in solvation energetics have been commonly proposed as a driving force for pressure-induced unfold...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4183293/ https://ncbi.nlm.nih.gov/pubmed/25201963 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1410655111 |
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