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Cavities determine the pressure unfolding of proteins
It has been known for nearly 100 years that pressure unfolds proteins, yet the physical basis of this effect is not understood. Unfolding by pressure implies that the molar volume of the unfolded state of a protein is smaller than that of the folded state. This decrease in volume has been proposed t...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3344970/ https://ncbi.nlm.nih.gov/pubmed/22496593 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1200915109 |
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