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Role of cavities and hydration in the pressure unfolding of T(4) lysozyme
It is well known that high hydrostatic pressures can induce the unfolding of proteins. The physical underpinnings of this phenomenon have been investigated extensively but remain controversial. Changes in solvation energetics have been commonly proposed as a driving force for pressure-induced unfold...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4183293/ https://ncbi.nlm.nih.gov/pubmed/25201963 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1410655111 |
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